首页   按字顺浏览 期刊浏览 卷期浏览 Dose‐response in infants receiving caudal anaesthesia with bupivacaine*
Dose‐response in infants receiving caudal anaesthesia with bupivacaine*

 

作者: R.M. SPEAR,  

 

期刊: Pediatric Anesthesia  (WILEY Available online 1991)
卷期: Volume 1, issue 1  

页码: 47-52

 

ISSN:1155-5645

 

年代: 1991

 

DOI:10.1111/j.1460-9592.1991.tb00009.x

 

出版商: Blackwell Publishing Ltd

 

关键词: anaesthetic techniques: caudal;anaesthetics local: bupivacaine;pharmacology: dose‐response

 

数据来源: WILEY

 

摘要:

Caudal epidural anaesthesia was performed in 25 awake or sedated infants, the sensory levels measured and the dose‐response determined (bupivacaine dose [ml kg−1] v. sensory level). The infants were divided into two groups based on body weight, group 1 (1.9–2.6 kg) and group 2 (3.4–7.0 kg). There was a significant difference between the dose‐response when comparing group 1 to group 2 (P<0.01). Smaller infants require a larger volume (ml kg−1) of local anaesthetic to achieve mid‐thoracic sensory levels than larger infants. In small infants, we recommend increasing the volume of local anaesthetic while still limiting the total bupivacaine dose to 3.25 mg kg−1by using 1.6 ml kg−1of bupivacaine 0.20% (3.20 mg kg−1) instead of 1.3 ml kg−1of bupivacaine

 

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