Dual Action of Electrochemical Stimulation of the Bed Nucleus of the Stria terminalis on the Release of LH
作者:
C. Beltramino,
S. Taleisnik,
期刊:
Neuroendocrinology
(Karger Available online 1980)
卷期:
Volume 30,
issue 4
页码: 238-242
ISSN:0028-3835
年代: 1980
DOI:10.1159/000123007
出版商: S. Karger AG
关键词: Ovulation;Hypothalamic afferents;Neural control
数据来源: Karger
摘要:
The effect of stimulation of the bed nucleus of the stria terminalis (BNST) on ovulation and LH release was studied in unanesthetized, freely moving rats. Electrochemical stimulation (anodic d.c, 100 µA/30 sec) was applied at i 1.30 h through chronically implanted monopolar, stainless steel electrodes. Serial blood samples were obtained by way of a plastic cannula implanted in the jugular vein. Stimulation on the day of proestrus prevented ovulation and the preovulatory discharge of LH when the stimulus was applied to the lateral part of the BNST but advanced the surge of LH in those rats stimulated in the medial part of the nucleus. In ovariectomized estrogen-primed rats stimulation in the medial part of the BNST produced LH release but no effect was seen when the stimulus was applied in the lateral part. It is concluded that the BNST is part of a dual system with antagonistic effects on LH secretion
点击下载:
PDF
(749KB)
返 回