Low Dose Alcohol Contracts the Human Umbilical Artery in Vitro
作者:
R. T. Savoy‐Moore,
M. P. Dombrowski,
A. Cheng,
E. A. Abel,
R. J. Sokol,
期刊:
Alcoholism: Clinical and Experimental Research
(WILEY Available online 1989)
卷期:
Volume 13,
issue 1
页码: 40-42
ISSN:0145-6008
年代: 1989
DOI:10.1111/j.1530-0277.1989.tb00281.x
出版商: Blackwell Publishing Ltd
数据来源: WILEY
摘要:
Beginning at very low concentrations (0.001 g/100 ml), alcohol elicited dose‐dependent contractions of the human umbilical artery in vitro. Additionally, 16 of the 108 arteries tested had a 5‐10‐min spasm in response to alcohol. Alcohol (0.2 91100 ml) also increased tension developed in response to all angiotensin II doses, but had no effect on serotonin‐induced contractions. These results suggest that alcohol may increase umbilicoplacental resistance in vivo, thus decreasing fetal‐placental b
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