The Biochemical Basis of Heart Failure
作者:
PoolPeter E.,
期刊:
Hospital Practice
(Taylor Available online 1971)
卷期:
Volume 6,
issue 2
页码: 83-94
ISSN:2154-8331
年代: 1971
DOI:10.1080/21548331.1971.11705991
出版商: Taylor&Francis
数据来源: Taylor
摘要:
As various pathways have been followed in the search for the biochemical defect underlying the onset of failure, evidence has been obtained that changes in energy metabolism and in protein synthesis may contribute but do not play the primary causative role. A third, more promising, possibility is that the defect may be in excitation-contraction coupling, specifically in the role of calcium as a mediator of contraction.
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