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Chemotherapy (CAP) for the Treatment of Advanced Ovarian Cancer and Second-Effort Surgery in the Second Look

 

作者: M.B. Ojeda-González,   I. Alvárez-López,   M.C. Alonso-Muñoz,   J. Badía-Serra,   E. Delgado-Latre,   L. de Andrés-Basauri,   J.J. López-López,  

 

期刊: Oncology  (Karger Available online 1991)
卷期: Volume 48, issue 1  

页码: 7-12

 

ISSN:0030-2414

 

年代: 1991

 

DOI:10.1159/000226885

 

出版商: S. Karger AG

 

关键词: Laparotomy, second-look;Second-effort surgery;Doxorubicin;Adriamycin;Cisplatin;Advanced ovarian cancer;Ovarian cancer, FIGO stages III and IV;Chemotherapy;Cyclophosphamide

 

数据来源: Karger

 

摘要:

Seventy-two patients with advanced ovarian cancer received CAP chemotherapy followed by laparotomy and ‘second-effort’ surgery. The overall response to CAP therapy was 80%. A complete pathological response (CPR) was obtained in 16 patients and partial microscopic (PMiR) and macroscopic responses in 7 and 33 cases, respectively. The actuarial survival for the entire group was 36% at 50 months with a median survival of 34 months. No significant differences in survival between the CPR and PMiR groups were found. Radical second-effort surgery showed a somewhat beneficial effect. The tumor size before chemotherapy ( < 5 cm) and FIGO stage III had a significantly favorable effect on response rate and survival.

 

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