Endolymph Formation in the Inner Ear of Pigeons
作者:
O. Ninoyu,
C. Hommerich,
C. Morgenstern,
期刊:
ORL
(Karger Available online 1987)
卷期:
Volume 49,
issue 1
页码: 1-8
ISSN:0301-1569
年代: 1987
DOI:10.1159/000275899
出版商: S. Karger AG
关键词: DC potentials;K+activity;Endolymph;Pigeons;Ethacrynic acid
数据来源: Karger
摘要:
The endolymphatic space of pigeons was studied by using double-barrelled electrodes with a potassium liquid ion exchanger. The K+ activity of the endolymph was 155 mM in the cochlea and 133 mM in the ampulla, respectively. Positive DC potential in the cochlea (+14.5 mV) was much lower than in guinea pigs (+80 mV) whereas in the ampulla of pigeons the DC potential (+7.4 mV) was 2 times higher than that of guinea pigs (+3.9 mV). General application of ethacrynic acid in pigeons induced a weak change in DC potential and no typical intercellular edema in the cochlea and ampulla. Local application of ethacrynic acid and ouabain in the cochlea and ampulla of pigeons induced a negative DC potential of between ––30 and ––40 mV. This negative DC potential was higher than the anoxia-induced negative potential. Short hypoxia during a drug-induced DC potential resulted in a decrease in DC potential above the diffusion potential. Below the diffusion potential additional hypoxia increased the DC potential independent of the cause of intox
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