Treatment of pain is common to all nurse practitioners' practices. One treatment method appropriate for use by the nurse practitioner is acupressure. Upon reviewing the professional literature, a paucity of information on acupressure was discovered. This article uses acupuncture theory and research to provide a theoretical basis for the use and study of acupressure. A description of how to locate and stimulate an acupoint useful for the treatment of headaches resulting from shoulder muscle tension is presented.