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Total Recovery of Infectious Virus from Noninfectious Type 1 Poliovirus-Antibody Complex by Heating in Salts

 

作者: Craig Wallis,   Anne Shirley,   Joseph L. Melnick,  

 

期刊: Intervirology  （Karger Available online 1973）
卷期: Volume 1, issue 1  

页码: 41-47

 

ISSN:0300-5526

 

年代: 1973

 

DOI:10.1159/000148831

 

出版商: S. Karger AG

 

关键词: Poliovirus;Neutralized virus;Virus-antibody dissociation;Virus-antibody complex

 

数据来源: Karger

 

摘要:

By heating neutralized mixtures of type 1poliovirus and antibody at 50° in 2 m Cad 2 or MgCl2, the virus could be dissociated from its antibody, and 100 %recovery of infectious virus could be achieved. Heating alone was not responsible for this phenomenon, sincecystine-stabilized thermoresistant polioviruses could not be recovered from neutralized mixtures by 50° treatment. Only 10 % recovery was achieved with other enteroviruse

 

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