Solid‐phase synthesis of the RNA fragment: rAAGAAGAAGAAGA
作者:
G. A. van der Marel,
G. Wille,
J. H. van Boom,
期刊:
Recueil des Travaux Chimiques des Pays‐Bas
(WILEY Available online 1982)
卷期:
Volume 101,
issue 7‐8
页码: 241-246
ISSN:0165-0513
年代: 1982
DOI:10.1002/recl.19821010703
出版商: WILEY‐VCH Verlag
数据来源: WILEY
摘要:
AbstractThe synthesis of the tridecaribonucleotide AAGAAGAAGAAGA on a polystyrene solid support via a phosphotriester approach is described. The assemblage of the oligomer was performed by four repeated coupling reactions of the partially protected trimer AAGp(3′) with an immobilized dimer in the presence of the activating agent (2,4,6‐triisopropylbenzenesulfonyl)‐3‐nitro‐1,2,4‐triazole. Purification of the RNA fragment was easily achieved by Sephadex G50 column chr
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