Nuclear Ploidy in Neuroendocrine Neoplasms of the Larynx
作者:
C.M. Milroy,
R.A. Williams,
I.G. Charlton,
E. Moss,
J. Rode,
期刊:
ORL
(Karger Available online 1991)
卷期:
Volume 53,
issue 4
页码: 245-249
ISSN:0301-1569
年代: 1991
DOI:10.1159/000276223
出版商: S. Karger AG
关键词: Larynx;DNA ploidy;Atypical carcinoid;Paraganglioma;Small cell neuroendocrine carcinoma
数据来源: Karger
摘要:
Seventeen neuroendocrine neoplasms of the larynx were examined for DNA ploidy. Twelve tumours were atypical carcinoids, four paragangliomas and one a small cell neuroendocrine carcinoma. Seven atypical carcinoids were aneuploid, one diploid and one tetraploid, with metastasis being aneuploid. In three cases only skin metastases were available for study, which were aneuploid. The small cell neuroendocrine carcinoma was aneuploid. Two of the paragangliomas were aneuploid and two diploid. Like other sites, neuroendocrine neoplasms of the larynx have a high rate of aneuploidy. Determination of DNA ploidy did not provide useful diagnostic or prognostic information.
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