Distribution of Group-Specific Component/Vitamin-D-Binding Protein Subtypes in Saudi Arabia
作者:
S.M. Degheishem,
S.H. Sedrani,
H. Van Baelen,
R. Bouillon,
A.S. Duhaiman,
期刊:
Human Heredity
(Karger Available online 1991)
卷期:
Volume 41,
issue 1
页码: 53-56
ISSN:0001-5652
年代: 1991
DOI:10.1159/000153974
出版商: S. Karger AG
关键词: Group-specific component;Vitamin-D-binding protein;Polymorphism;Population study;Saudi Arabia
数据来源: Karger
摘要:
The distribution of group-specific component (Gc) phenotypes and the Gc allele frequencies were investigated in 1,082 individuals from five different provinces of Saudi Arabia by the combined use of isoelectric focusing and immunofixation. Between provinces variations in the Gc allele frequencies were found. Gc1S decreased and Gc1F increased from the northwest to the southeast in Saudi Arabia. The overall frequencies in Saudi Arabia were 0.236 for Gc1F, 0.610 for Gc1s, 0.150 for Gc2 and 0.004 for rare alleles. The observed frequencies did not differ significantly from those found in other population samples from the Middle East. In nine samples rare Gc variants were found.
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