We study the lasing behavior and photo induced quenching of dye doped polystyrene microspheres with diameter ranging from 10 μ to 92μ. Lasing of the spherical cavity modes is clearly observed. Emission from individual sphere placed on a glass plate is examined under the pumping of nanosecond pulses which are tuned to the absorption band of the dye. Intensity of each lasing line is strictly controlled by additional irradiation of monochromatic laser which can couple to resonance modes of the cavity. The line intensity plummets down when the additional beam frequency matches to the resonances of the modes which have the same radial profile of relevant mode.