Piezoelectric Detection of Ricin and Affinity-Purified Goat Anti-ricin Antibody
作者:
R.M. Carter,
M.B. Jacobs,
G.J. Lubrano,
G.G. Guilbault,
期刊:
Analytical Letters
(Taylor Available online 1995)
卷期:
Volume 28,
issue 8
页码: 1379-1386
ISSN:0003-2719
年代: 1995
DOI:10.1080/00032719508006401
出版商: Taylor & Francis Group
关键词: Ricin;Anti-Ricin;Piezoelectric;Biosensor;Detection
数据来源: Taylor
摘要:
Detection of ricin, in a piezoelectric quartz crystal microbalance format, can be accomplished with the use of capture antibody techniques. These techniques allow for the specific attachment of ricin to immobilized capture antibodies on the quartz crystal transducer area. A reversed format can also be used to detect antibody in solution. In this case, the antigen is immobilized and antibody attaches specifically, thus increasing the overall mass and decreasing the resonant frequency. In this report we describe detection of both ricin and anti-ricin antibody using immunological piezoelectric quartz crystal microbalance techniques.
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