A Clinicopathologic Study of Six Cases of Lipoid Proteinosis
作者:
Gérald Piérard,
Dominique Cauwenberge,
José Budo,
Charles Lapière,
期刊:
The American Journal of Dermatopathology
(OVID Available online 1988)
卷期:
Volume 10,
issue 4
页码: 300-305
ISSN:0193-1091
年代: 1988
出版商: OVID
关键词: Lipoid proteinosis;Basement membrane components;Immunohistochemistry
数据来源: OVID
摘要:
We have reviewed the clinical and histological presentations of six cases of lipoid proteinosis. Deposits in the dermis were heterogeneous in nature and location. In the first stage of the disease's evolution, basement membrane components accumulate at the normal site of vascular, muscular, and epithelial basement membranes. Later on, lipids and amorphous material fill the superficial dermis, pushing apart the normal collagen bundles. Such deposits seem to be organized around preserved reticulin fibers. The amorphous material did not react with antibodies to collagen types I, III, IV, and V.
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