Fluconazole-ResistantCryptococcus NeoformansVarGattiiin an Aids Patient
作者:
PeetermansW.,
BobbaersH.,
Verhaegen*J.,
VandepitteJ.,
期刊:
Acta Clinica Belgica
(Taylor Available online 1993)
卷期:
Volume 48,
issue 6
页码: 405-409
ISSN:1784-3286
年代: 1993
DOI:10.1080/17843286.1993.11718338
出版商: Taylor&Francis
数据来源: Taylor
摘要:
SummaryWe describe a case of meningitis due to Cryptococcus neoformans var gattii in an AIDS patient. The reasons for the observed predominance of C.neoformans var neoformans infections in AIDS patients living in areas endemic for the gattii variety are not understood thus far.Treatment with fluconazole resulted in poorclinical and mycological response. In vitro sensitivity testing of the fungus revealed high minimal inhibitory concentrations, suggesting fluconazole resistance. Treatment with amphotericin B was successful.
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