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Anatomic Staging Systems for Cancer Fixed End‐Point Survival Rates and Tort Claims

 

作者: John Spratt,  

 

期刊: Journal of Pelvic Surgery  (OVID Available online 1995)
卷期: Volume 1, issue 1  

页码: 8-11

 

ISSN:1077-2847

 

年代: 1995

 

出版商: OVID

 

数据来源: OVID

 

摘要:

ObjectiveThe objectives of the report are to show the intrinsic biases that exist in fixed end-point (5-year and 10-year survival rates) when related to the TNM staging system. The biases are reduced when survival data are reported as forces of mortality. These biases yield false expectations and prednispose to tort claims.ResultsThe intrinsic biases in comparing the benefit of cancer control strategies by TNM stage specific fixed end-point (i.e., 5-year and 10-year) survival rates predisposes treating physicians to tort claims. How variable growth rates and variable biologic propensity to metastasize introduce both length bias and lead time bias is presented. Effective cancer control is documented only when the population based age specific mortality rate declines, or when the treated patients exhibit a decrease in the force of mortality associated with individual cancer co-mortality variables. Only when the force of mortality associated with invasive breast cancer is brought to parallel the expected mortality, can a statistical cure be concluded. No study has ever confirmed that a statistical cure for invasive breast cancer has been attained. Breast cancer is used as a model but the principles apply to many other forms of cancer.

 

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