Children with developmental disabilities are at high risk for malnutrition. Severe nutritional problems can be prevented through routine screening, timely assessment, and appropriate intervention. This article outlines the process of nutritional screening to identify children with potential problems, describes the components of a comprehensive nutritional assessment for the disabled child, and presents nutritional intervention strategies for five problems common in the disabled population: poor growth and failure to thrive, overweight and obesity, feeding problems, constipation, and drug-nutrient interactions.