To solve some of the problems inherent in bone regeneration, various types of graft materials, matrix, putty, and gel delivery systems have been developed. These deliver demineralized bone matrix (DBM) to a graft site and maintain it in an appropriate position to achieve favorable results. This prospective study reviewed 10 cases of extraction immediate grafting with a putty–DBM delivery system. Five patients were male and 5 female. At intervals ranging from 4 to 21 months postextraction grafting, bone cores were harvested at the time of surgical insertion of Replace endosteal two-stage implants. All patients were restored with single-tooth self-standing prostheses. Bone quality and quantity in each of the bone cores were evaluated. All 10 cases were completed with favorable outcomes.