首页   按分类浏览 期刊浏览 卷期浏览 A Short and Convenient Synthesis of 5-Alkyl Substituted 8-Hydroxyquinolines
A Short and Convenient Synthesis of 5-Alkyl Substituted 8-Hydroxyquinolines

 

作者: Massoud Hojjatie,   Subramaniam Muralidharan,   MarkL. Dietz,   Henry Freiser,  

 

期刊: Synthetic Communications  （Taylor Available online 1989）
卷期: Volume 19, issue 13-14  

页码: 2273-2282

 

ISSN:0039-7911

 

年代: 1989

 

DOI:10.1080/00397918908052626

 

出版商: Taylor & Francis Group

 

数据来源: Taylor

 

摘要:

5-Chloro-8-methoxyquinoline undergoes rapid and reversible lithium-halogen exchange reaction with alkyllithiums to yield 5-alkyl substituted derivatives indirectly, whereas the reaction with phenyllithium is slower and 5-alkyl substituted compounds are formed by the direct addition of alkyl halides.

 

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