Laser‐Assisted Reconstruction of the Oculomotor Nerve: Experimental Study on the Feasibility of Cranial Nerve Repair
作者:
Volker Seifert,
Dietmar Stolke,
期刊:
Neurosurgery
(OVID Available online 1989)
卷期:
Volume 25,
issue 4
页码: 579-583
ISSN:0148-396X
年代: 1989
出版商: OVID
关键词: Cranial nerves;Laser surgery;Nerve anastomosis
数据来源: OVID
摘要:
&NA;In this experimental study the feasibility of microsurgical laser‐assisted repair of the oculomotor nerve in the cat was investigated. The 3rd cranial nerve was explored after a temporobasal craniectomy from its exit at the brain stem to its entrance into the cavernous sinus and transected. The cut nerve ends were loosely reapproximated and welded together with a CO2milliwatt laser using a power setting of 80 to 90 mW and a spot size of 150 &mgr;. Regeneration of the oculomotor nerve within an observation period of 12 months as assessed by weekly examination of the pupil diameter was excellent in 4 animals and satisfactory in 2. In the two control groups consisting of 6 animals in which the nerve reconstruction had been performed with fibrin glue or by simple nerve reapproximation minimal nerve regeneration could be observed only in one animal. The histomorphological examinations revealed good regeneration across the laser anastomosis including new formation of a perineural sheath without any significant scarring effect or constriction at the anastomotic site. It is concluded that the CO2milliwatt laser might be a useful tool for the microsurgical repair of cranial nerves and should possibly be incorporated into the neurosurgical armamentarium of reconstructive cranial nerve surgery. (Neurosurgery25:579‐583,1989)
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