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No treatment option for liver metastases from colorectal adenocarcinoma

 

作者: Michael Palmer,   Nicholas Petrelli,   Lemuel Herrera,  

 

期刊: Diseases of the Colon & Rectum  (OVID Available online 1989)
卷期: Volume 32, issue 8  

页码: 698-701

 

ISSN:0012-3706

 

年代: 1989

 

出版商: OVID

 

关键词: Metastases;Liver;Adenocarcinoma

 

数据来源: OVID

 

摘要:

&NA;After an explanation of alternative treatment modalities, 30 patients with unresectable liver metastases from colorectal adenocarcinoma chose to have no treatment. Fourteen patients (47 percent) had synchronous liver metastases and 16 (53 percent) had metachronous lesions. Thirteen of the 30 patients (43 percent) had histologic documentation of liver metastases, with the remaining 17 patients diagnosed by liver scan, ultrasonography, or computerized axial tomography. Twenty‐four of 30 patients (80%) had less than 25 percent liver involvement (Stage I), 23 of 24 patients had alkaline phosphatase levels less than twice normal, and 20 of 24 patients were asymptomatic from their liver metastases. The remaining six patients had liver stages II or III at the time of diagnosis. Overall mean survival of the 30 reported patients with untreated metastatic colorectal cancer to liver is 16 months (range, 2 to 58 months; median survival, 12 months).

 

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