Sulfur belongs to the main crosslinking components in rubber mixes and hence its great effect on the product properties obtained. It is therefore extremely important to recognize the movement and distribution of sulfur during the process as its static and dynamic properties depend on heterogeneity of space crosslinking of the vulcanizate. In the present paper the radioisotope method of investigation of sulfur distribution and dispersion in rubber mixes has been discussed and examples of interpretation of the results obtained in experiments have been given.