Comparative Efficacy of Short-Term Versus Long-Term Cefoxitin Prophylaxis Against Postoperative Infection After Radical Hysterectomy: A Prospective Study
作者:
BERND-UWE SEVIN,
REINALDO RAMOS,
ROBERT GERHARDT,
LUCY GUERRA,
SUSAN HILSENBECK,
HERVY AVERETTE,
期刊:
Obstetrics & Gynecology
(OVID Available online 1991)
卷期:
Volume 77,
issue 5
页码: 729-734
ISSN:0029-7844
年代: 1991
出版商: OVID
数据来源: OVID
摘要:
We report the results of a randomized, double-blind comparison of short-term versus long-term cefoxitin prophylaxis against infections after radical abdominal hysterectomy with pelvic and para-aortic lymphadenectomy. Of 113 evaluable patients, 54 (47.8%) received short-term (three doses) and 59 (52.2%) long-term (12 doses) prophylaxis with intravenous cefoxitin (2 g per dose). No significant differences demographics, preoperative risk factors, or clinical course were detected between the two groups; nor did we detect significant differences in the incidence of surgical-siterelated infections (7.4 versus 5.1%, respectively,P=.61), postoperative urinary tract infection, or other febrile morbidity. We conclude that short-term and long-term cefoxitin prophylaxis are equally effective for the prevention of postoperative surgical-site-related infections after radical hysterectomy.
点击下载:
PDF
(489KB)
返 回