REVERSED PHASE CHROMATOGRAPHIC STUDY OF THE INCLUSION SELECTIVITY OF TERPENE DERIVATIVES WITH β-CYCLODEXTRIN IN WATER/COSOLVENT MIXTURES
作者:
AlexisK. Chatjigakis,
Igor Clarot,
PhilippeJ. P. Cardot,
Robert Nowakowski,
Anthony Coleman,
期刊:
Journal of Liquid Chromatography & Related Technologies
(Taylor Available online 1999)
卷期:
Volume 22,
issue 9
页码: 1267-1284
ISSN:1082-6076
年代: 1999
DOI:10.1081/JLC-100101731
出版商: Taylor & Francis Group
数据来源: Taylor
摘要:
Terpene compounds include a wide variety of molecules with very different structures and physico-chemical properties. Monoterpenes are of interest because of their volatility and aromatic properties. Inclusion complexation of these molecules with cyclodextrins will lead to chemical and volatility protection and to a possible controlled release. In this study, reversed phase liquid chromatography was used to demonstrate that some terpenes can form inclusion complexes with β-cyclodextrin. The stability of these complexes was studied for aromatic, aliphatic, or acyclic terpenes with various mobile phases.
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