首页   按字顺浏览 期刊浏览 卷期浏览 Fc-Receptor Function of the Mononuclear Phagocyte System in Glomerulonephritis Secondar...
Fc-Receptor Function of the Mononuclear Phagocyte System in Glomerulonephritis Secondary to Some Multisystem Diseases

 

作者: Dario Roccatello,   Rosanna Coppo,   Guido Martina,   Cristiana Rollino,   Bruno Basolo,   Clelia Frattasio,   Maria Edvige Fasano,   Antonio Amoroso,   Giuseppe Picciotto,   Pietro Bajardi,   Daniel Cordonnier,   Giuseppe Piccoli,  

 

期刊: American Journal of Nephrology  （Karger Available online 1987）
卷期: Volume 7, issue 2  

页码: 85-92

 

ISSN:0250-8095

 

年代: 1987

 

DOI:10.1159/000167441

 

出版商: S. Karger AG

 

关键词: Mononuclear phagocyte system;Fc-receptor function;Lupus nephritis;Vasculitis;Cryoglobulinemia

 

数据来源: Karger

 

摘要:

The Fc-receptor function of the mononuclear phagocyte system was examined in 30 patients affected by multisystem diseases with glomerular involvement by measuring the immune clearance of IgG-sensitized autologous red blood cells in vivo and the immune phagocytosis of monocytes in vitro. Patients studied in the phase of clinically active renal disease showed a significantly reduced Fc-receptor function by both in vivo (p < 0.001) and in vitro (p = 0.003) assays, as compared to those studied during an inactive phase. Though the nature of the defect remains uncertain, it appears to be related to the active phase of the renal disease as also confirmed by the analysis of individual cases studied longitudinally.

 

点击下载:  PDF (1496KB)



返 回