首页   按字顺浏览 期刊浏览 卷期浏览 IgG antibody and antibody–antigen complex imaging by scanning tunneling microscopy
IgG antibody and antibody–antigen complex imaging by scanning tunneling microscopy

 

作者: Charles H. Olk,   Joseph Heremans,   Peter S. Lee,   Daniel Dziedzic,   Nicholas E. Sargent,  

 

期刊: Journal of Vacuum Science&Technology B: Microelectronics and Nanometer Structures Processing, Measurement, and Phenomena  （AIP Available online 1991）
卷期: Volume 9, issue 2  

页码: 1268-1271

 

ISSN:1071-1023

 

年代: 1991

 

DOI:10.1116/1.585218

 

出版商: American Vacuum Society

 

关键词: ANTIBODIES;ANTIGENS;COMPLEXES;GOLD;IMAGES;SCANNING TUNNELING MICROSCOPY;MOLECULAR STRUCTURE

 

数据来源: AIP

 

摘要:

We have examined two preparations of biomolecules labeled with colloidal gold markers using scanning tunneling microscopy. In the first preparation, we studied gold labeled IgG antibodies. In the second preparation, we studied unlabeled IgG antibodies which were complexed with gold labeled antigen (bovine serum albumin). Images of these noncrystalline biological specimens, obtained under atmospheric conditions, revealed features on a nanometer scale. The images show details of molecular organization in addition to the classical antibody configuration.

 

点击下载:  PDF (446KB)



返 回