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In VitroAnti‐Mycobacterium aviumActivity ofN‐(2‐Hydroxyethyl)‐1,2‐benzisothiazol‐3(2H)‐one and ‐thione Carbamic Esters

 

作者: Giuseppe Pagani,   Pietro Borgna,   Claudio Piersimoni,   Domenico Nista,   Marco Terreni,   Massimo Pregnolato,  

 

期刊: Archiv der Pharmazie  （WILEY Available online 1996）
卷期: Volume 329, issue 8‐9  

页码: 421-425

 

ISSN:0365-6233

 

年代: 1996

 

DOI:10.1002/ardp.19963290810

 

出版商: WILEY‐VCH Verlag

 

关键词: N‐[2‐[(N‐alkylcarbamoyl)oxy]ethyl]‐1,2‐benzisothiazol‐3(2H)‐ones;N‐[2‐[(N‐alkylcarbamoyl)oxy]ethyl]‐1,2‐benzisothiazol‐3(2H)‐thiones;Mycobacterium avium;anti‐Mycobacterium activity

 

数据来源: WILEY

 

摘要:

AbstractA series ofN‐(2‐hydroxyethyl)‐1,2‐benzisothiazol‐3(2H)‐one and ‐thione carbamic esters have been synthesised and tested againstMycobacterium aviumstrains. The MIC values determined by the radiometric broth dilution method were between 2 and 8 μg/mL for the benzisothiazolthione derivatives and between 16 and 32 μg/mL or higher for the corresponding benzisothiazol

 

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