Using xeroradiographic techniques, both metacarpophalangeal regions of six quarter horse foals were radiographed at 1 day of age and at 2‐week intervals until they were 6 weeks old, and then at 4‐week intervals until they were 12 months old. Lateromedial and dorsopalmar xeroradiographs of each metacarpophalangeal region were made per examination; dorsomedial‐palmarolateral projections of the left metacarpophalangeal joint of foal 6 were also made. The foals were weighed and measured at the withers immediately prior to each examination. Representative xeroradiographs were selected to demonstrate progression of the osteochondrosis (OCH) lesions in two of these foals. Radiographic evidence of osteochondrosis in the metacarpophalangeal region was first detected at 10 weeks and followed through 12 months of age. In one foal the lesions were bilaterally symmetric and involved the dorsoproximal aspect of the sagittal ridge of metacarpal 3; in the other, the left medial proximal sesamoid bone was affected. One of the sagittal ridge lesions progressed to osteochondritis dissecans by 26 weeks; the other sagittal ridge lesion and that of the sesamoid bone healed spontaneously, but residual radiographic evidence of the disease persisted throughout the study in both