首页   按字顺浏览 期刊浏览 卷期浏览 Comparison of Double‐burst and Train‐of-four Stimulation to Assess Neurom...
Comparison of Double‐burst and Train‐of-four Stimulation to Assess Neuromuscular Blockade in Children

 

作者: J.,   Saddler J.,   Bevan F.,   Donati D.,   Bevan S.,  

 

期刊: Anesthesiology  (OVID Available online 1990)
卷期: Volume 73, issue 3  

页码: 401-403

 

ISSN:0003-3022

 

年代: 1990

 

出版商: OVID

 

关键词: Anesthesia;pediatric;Monitoring;neuromuscular junction;double burst stimulation;train-of-four stimulation.;Neuromuscular relaxants;atracurium.;Neuromuscular transmission;double burst;train-of-four.

 

数据来源: OVID

 

摘要:

Double-burst stimulation (DBS), a new technique to evaluate neuromuscular function, consists of two 50-Hz trains of 60-ms duration and 750 ms apart. DBS was compared with train-of-four (TOF) stimulation in 21 children aged 3–10 yr, during halothane anesthesia. On one arm the ulnar nerve was stimulated supramaximally with TOF stimulation every 12 s and the force of the evoked contraction of the adductor pollicis measured with an FTO3 force transducer and recorded on paper. Atracurium (0.4–0.5 mg · kg−1) was administered. During recovery from neuromuscular blockade, TOF stimulation was interrupted periodically and DBS substituted. The same stimulation patterns were applied to the ulnar nerve of the other arm simultaneously, and the clinical anesthesiologist was asked to estimate the degree of fade with both. There was good correlation between the measured TOF ratio (ratio of fourth to first response) and DBS ratio (ratio of second to first response). The TOF and DBS ratios above which fade could no longer be appreciated manually were (mean ± SEM) 0.44 ± 0.03 and 0.67 ± 0.04 (P= 0.0002). Corresponding ranges were 0.3–0.8 for TOF and 0.4–0.9 for DBS, but DBS fade was always apparent if TOF fade could be detected. Therefore, in children, DBS is more sensitive than is TOF stimulation for the clinical assessment of recovery from neuromuscular blockade.

 

点击下载:  PDF (208KB)



返 回