The behavior of acids on the layers of cellulose and silica gel was studied. The samples used were HCl and HClO4, and the developers were water, acetone, ethanol, and n-butanol. Monitored, was also the behavior of HCl as a component of the developers water-HCl and n-butanol-HCl. The results have shown that acids are strongly sorbed on the layers of silica gel and cellulose. Hydrogen ion and an anion of strong inorganic acids behaved differently on sorbent layer; generally H+ion was stronger sorbed than A−ion. Sorption and behavior of acid ions depended on the properties of a sorbent, solvent and acid, i. e. on an interaction of all components of the chromatographic system.