Effect of Secretin on Mucinous Secretion by the Isolated Canine Stomach Perfused Extracorporeally
作者:
K. Kowalewski,
T. Pachkowski,
A. Kolodej,
期刊:
Pharmacology
(Karger Available online 1978)
卷期:
Volume 16,
issue 2
页码: 78-82
ISSN:0031-7012
年代: 1978
DOI:10.1159/000136750
出版商: S. Karger AG
关键词: Amino acids;Ex vivoperfusion;Gastric mucin;Glycoproteins;Isolated canine stomach;Pentagastrin;Secretin;Uronic acid
数据来源: Karger
摘要:
Principal glycoproteins, uronic acid and amino acids were determined in canine gastric secretion, obtained from isolated canine stomachs perfused extracorporeally with homologous blood. Gastric secretion was collected during intraarterial infusion of pentagastrin alone for 3 h, and of secretin + pentagastrin for the next 3 h. Secretin produced a significant increase in the output of D-galactose, D-glucosamine, L-fucose, D-glucose, total sugars, total sulfate and uronic acid. Secretin had no significant effect on the output of most of amino acids of gastric secretion.
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