首页   按字顺浏览 期刊浏览 卷期浏览 Experience with the [13C2]Oxalate Absorption Test
Experience with the [13C2]Oxalate Absorption Test

 

作者: G.E. Von Unruh,   S. Voss,   A. Hesse,  

 

期刊: Isotopes in Environmental and Health Studies  (Taylor Available online 2000)
卷期: Volume 36, issue 1  

页码: 11-20

 

ISSN:1025-6016

 

年代: 2000

 

DOI:10.1080/10256010008032929

 

出版商: Taylor & Francis Group

 

关键词: Absorption;Carbon 13;function test;oxalate;urinary stones;urine test

 

数据来源: Taylor

 

摘要:

Hyperoxaluria is the most important risk factor for a formation of calcium oxalate-urinary stones. Usually, the bulk of oxalate will be formed in the human body, but in many patients the oxalate from food plays the decisive role. Conventionally, in urine the endogenous oxalate can not be distinguished from food derived oxalate. We have developed a standardized oxalate-absorption test, applying a physiological dose (50 mg disodium salt of [13C2]oxalic acid) of labelled oxalate. The assay has been published. Now we report on the first extensive applications of this test in 86 volunteers and 135 patients from different groups with calcium oxalate stones or an increased risk of the formation of such stones. In one-third of the patients with calcium oxalate-urinary stones an oxalate hyperabsorption was diagnosed. For these patients, a dietetic stone prophylaxis and/or therapy is indicated.

 

点击下载:  PDF (356KB)



返 回