Experience with the [13C2]Oxalate Absorption Test
作者:
G.E. Von Unruh,
S. Voss,
A. Hesse,
期刊:
Isotopes in Environmental and Health Studies
(Taylor Available online 2000)
卷期:
Volume 36,
issue 1
页码: 11-20
ISSN:1025-6016
年代: 2000
DOI:10.1080/10256010008032929
出版商: Taylor & Francis Group
关键词: Absorption;Carbon 13;function test;oxalate;urinary stones;urine test
数据来源: Taylor
摘要:
Hyperoxaluria is the most important risk factor for a formation of calcium oxalate-urinary stones. Usually, the bulk of oxalate will be formed in the human body, but in many patients the oxalate from food plays the decisive role. Conventionally, in urine the endogenous oxalate can not be distinguished from food derived oxalate. We have developed a standardized oxalate-absorption test, applying a physiological dose (50 mg disodium salt of [13C2]oxalic acid) of labelled oxalate. The assay has been published. Now we report on the first extensive applications of this test in 86 volunteers and 135 patients from different groups with calcium oxalate stones or an increased risk of the formation of such stones. In one-third of the patients with calcium oxalate-urinary stones an oxalate hyperabsorption was diagnosed. For these patients, a dietetic stone prophylaxis and/or therapy is indicated.
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