A number of ethical issues have been created by the possibility of transplanting organs from anencephalic infants to other children who need an organ in order to live. The issues of moral justification of the practice, adequacy of informed consent procedures involved, and the potential constraints on female integrity are explored and the relevant arguments for and against transplantation efforts are discussed. Nurses are encouraged to become knowledgeable about the issues and to enter into public discussion of the issues as policy initiatives are proposed.