AbstractPolymers containing theN‐(4‐hydroxy‐3‐nitrophenyl)succinimide residue were designed in order to achieve acyl activation of a reacting carboxylic acid in the solid phase. These polymers were prepared through the following three routes: (a) styrene was allowed to copolymerize withN‐(4‐hydroxy‐3‐nitrophenyl)‐ orN‐(4‐acetoxy‐3‐nitrophenyl)maleimide, (b) styrene was copolymerized withN‐(4‐acetoxyphenyl)maleimide in the presence of divinylbenzene (DVB), and the copolymer obtained was hydrolyzed and nitrated, (c) a copolymer of maleic anhydride and styrene was reacted withp‐aminophenol, followed by nitration. The polymers prepared by routes b and c were converted to the activated polymer esters ofN‐blocked amino acids and peptides by using dicyclohexylcarbodiimide (DCC). The acylated polymers thus obtained were treated with amino acid esters and found to give peptides qu