Liquid chromatographic determination of uric acid and ascorbic acid in rat retinae after ophthalmic artery and optic nerve ligation
作者:
IriyamaKeiji,
YoshiuraMasahiko,
IwamotoTakeo,
KamadaYoshio,
NozawaHiroko,
MizunoAritake,
MatsuzakiHiroshi,
期刊:
Current Eye Research
(Taylor Available online 1986)
卷期:
Volume 5,
issue 7
页码: 479-483
ISSN:0271-3683
年代: 1986
DOI:10.3109/02713688608996369
出版商: Taylor&Francis
数据来源: Taylor
摘要:
Change of urate and ascorbate levels in retinae of rat left eyes after ophthalmic artery and optic nerve ligation was studied by reversed-phase high-performance liquid chromatography with electrochemical detection. The right eyes were used for sham operation. We found that uric acid levels in the retinae of the left eyes increased as a function of time after the operation, whereas those of the right eyes remained unchanged. In addition, we found that ascorbic acid levels in the retinae of the rat eyes decreased after the operation.
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