首页   按字顺浏览 期刊浏览 卷期浏览 Cross‐reaction in allergic contact dermatitis from α‐methylene‐γ‐butyrolactones: import...
Cross‐reaction in allergic contact dermatitis from α‐methylene‐γ‐butyrolactones: importance of thecisor trans ring junction

 

作者: Marcel Schaeffer,   Patrice Talage,   Jean‐Luc Stampf,   Claude Benezra,  

 

期刊: Contact Dermatitis  （WILEY Available online 1990）
卷期: Volume 22, issue 1  

页码: 32-36

 

ISSN:0105-1873

 

年代: 1990

 

DOI:10.1111/j.1600-0536.1990.tb01502.x

 

出版商: Blackwell Publishing Ltd

 

关键词: cross‐sensitivity;α‐methylene‐γ‐butyolactones;sesquiterpene lactones;bicyclic lactones;guinea pig sensitization;modifies FCAT method;stereospecificity;cisortransring junctions

 

数据来源: WILEY

 

摘要:

Cross‐reaction in allergic contact dermatitis (ACD) is a highly stereoselective process. The importance of thecisortransring junction in α‐methylene‐γ‐butyrolactones in cross‐reactivity was investigates by reacting Helenin® (mostly a mixture of natural allergenic sesquiterpene lactones alantolactone1and isoalantolactone2, which present acisring junction) in guinea pigs sensitized to model allergenic α‐methylene‐γ‐butyolactones:cis‐bicyclin lactone3and

 

点击下载:  PDF (464KB)



返 回