Immunoelectron microscopic localization of cytochrome P‐450 isoenzyme CYP4A1 in liver, ileum and kidney of nafenopin treated male rats.
作者:
Elke Persohn,
Helmut Thomas,
Felix Waechter,
期刊:
Cell Biology International
(WILEY Available online 1993)
卷期:
Volume 17,
issue 1
页码: 99-103
ISSN:1065-6995
年代: 1993
DOI:10.1006/cbir.1993.1010
出版商: Blackwell Publishing Ltd
数据来源: WILEY
摘要:
AbstractA monoclonal antibody raised against and specific for cytochrome P‐450 isoenzyme CYP4A1 was used to investigate the subcellular distribution of this enzyme in the liver, kidney and ileum of nafenopin treated rats by means of immunoelectron microscopy. In the liver and kidney, labelling was restricted to peroxisomes and mitochondria of hepatocytes and proximal tubular epithelial cells whereas in ileum, immunolabelling was exclusively detected in mitochondria of absorptive cell
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