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Cephalothin, cefoxitin, or metronidazole in elective colonic surgery?A single‐blind randomized trial

 

作者: G.,   Panichi A.,   Pantosti G.,   Giunchi F.,   Tonelli P.,   D'Amicis G.,   Fegiz Gianfrilli,   Mastrantonio I.,   Luzzi M.,  

 

期刊: Diseases of the Colon & Rectum  （OVID Available online 1982）
卷期: Volume 25, issue 8  

页码: 783-786

 

ISSN:0012-3706

 

年代: 1982

 

出版商: OVID

 

关键词: Surgery colorectal;Cephalothin;Cefoxitin;Metronidazole;Infection;Sepsis

 

数据来源: OVID

 

摘要:

&NA;A randomized controlled trial aimed at comparing the individual efficacy of cephalothin, cefoxitin, and metronidazole in the prevention of postoperative wound infection was performed among 74 colorectal surgical patients. Of 28 patients on cephalothin, seven (25 per cent) developed a postoperative infection, but among 23 patients in each of the other two groups, only one (4 per cent) in each group became infected. These results confirm the primary importance of anaerobes in the causation of postoperative sepsis after colorectal surgery.

 

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