AbstractExtracellular matrix (ECM) proteins form distinct proteinfamilies that play a role during tissue maturation, wound healing and maintenance of tissue architecture. Recent studies show that there are tissue type ‐specific variations in their expression. ECM proteins function by complexing with each other and also by interacting with their cellular receptors, called integrins. Integrins are heterodimeric membrane.glycoproteins that are partly cell type ‐specifically expressed in human tissues. Like other stratified epithelia, corneal epithelium expresses α2β1, α3β1, α6β1,4, and αvβ1integrins that mediate attachment to the basement membrane and cell‐cell