Near surface and bulk radiation enhanced self-diffusion of Ni0.3in nickel was measured after irradiations with 2 MeV electrons. In the temperature range between 550 and 800°K the bulk diffusion coefficient is DRad= 1.347 × 10−12exp (-0.41/kT cm2/s) for a flux of 20 μA/cm2. The measured diffusion coefficients are at least two orders of magnitude larger than those predicted by theories based either on the one- or the two- interstitial model. This discrepancy between experiment and theory is resolved for the two-interstitial model by considering the interactions between sell-interstitials and vacancies during their life times. These interactions led to an effective migration energy of self-interstitials ofEMeff, = 0.82 eV. which is smaller thanEM=1.0 eV. The experimental data can be described by DRadα2nf(Kvell1)12.