Viral Persistence and Immune Dysfunction
作者:
OldstoneMichael B. A.,
期刊:
Hospital Practice
(Taylor Available online 1990)
卷期:
Volume 25,
issue 5
页码: 81-98
ISSN:2154-8331
年代: 1990
DOI:10.1080/21548331.1990.11703948
出版商: Taylor&Francis
数据来源: Taylor
摘要:
Viruses can persist for years without provoking an effective host immune response or otherwise causing the cell destruction characteristic of an acute viral infection. Clinically relevant principles, generalizable to many persistent viruses, are exemplified by measles and lymphocyte choriomeningitis viruses. The LCMV model indicates that viral persistence and the anergic state are reversible.
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