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Silicon Nephropathy: a Possible Occupational Hazard

 

作者: D. Hauglustaine,   B. Van Damme,   P. Daenens,   P. Michielsen,  

 

期刊: Nephron  （Karger Available online 1980）
卷期: Volume 26, issue 5  

页码: 219-224

 

ISSN:1660-8151

 

年代: 1980

 

DOI:10.1159/000181988

 

出版商: S. Karger AG

 

关键词: Silica inhalation;Glomerulotubular damage;Toxic nephropathy;Occupational hazard

 

数据来源: Karger

 

摘要:

A 37-year-old white male, working in a tile factory, presented proteinuria with no obvious tubular dysfunction. Renal biopsy disclosed a mild focal segmental proliferative glomerulonephritis. Distinct alterations were found by electron microscopy, especially in the proximal tubular cells. Because of a history of heavy dust exposure the silicon content was determined in the kidney biopsy tissue. The finding of 150 mg/kg silicon on tissue dry weight supports the diagnosis of silicon nephropathy.

 

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