Antibiotics, Agrimycin 100, Agrimycin 500, Agric. Terramycin 17, A.S. 50 and Streptocycline, and fungicides, Brestanol, Fytolan and Vitavax, were evaluated under field conditions for control of bacterial leaf blight of rice caused byXanthomonas oryzae. Agric. Terramycin 17, Brestanol, Agrimycin 500 and a combination of Agrimycin 100 + Fytolan gave effective control of the blight phase of the disease. The combination of Agrimycin 100 + Fytolan spraying gave good control of the disease and an economic return on susceptible varieties like Sona.