A NewαChain Variant, HB Turriff [α99(66)LYS→6LU]: The Interference of Abnormal Hemoglobins in HB A1CDetemination
作者:
LangdormJ. V.,
DavidsonR. J. L.,
WilliamsonD.,
期刊:
Hemoglobin
(Taylor Available online 1992)
卷期:
Volume 16,
issue 1-2
页码: 11-17
ISSN:0363-0269
年代: 1992
DOI:10.3109/03630269209005671
出版商: Taylor&Francis
数据来源: Taylor
摘要:
Hb Turriff is a new hemoglobin variant which we have identified in a diabetic individual. During the determination of Hb A by high performance liquid chromatography, an inappropriately elevated result was found to be due to the abnormal hemoglobin chromatographing with the Hb A1cfraction. This new hemoglobin variant, Hb Turriff [α99(66)Lys→Glu), is not associated with any hematological disturbance, and family investigations indicate that it has arisen as a de novo mutation.
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