The effect of near-UV light on Na-K-ATPase of the rat lens
作者:
TorrigliaAlicia,
ZigmanSeymour,
期刊:
Current Eye Research
(Taylor Available online 1988)
卷期:
Volume 7,
issue 6
页码: 539-548
ISSN:0271-3683
年代: 1988
DOI:10.3109/02713688809031809
出版商: Taylor&Francis
数据来源: Taylor
摘要:
The influence ofin vitronear-UV radiation exposure on the physical state of the rat lens and on its membrane-bound Na-K-ATPase activity was investigated. Lens swelling was correlated to the appearance of opacities and the inactivation of the enzyme. The results show a significant decrease in the Na-K-ATPase activity which may be an early change leading to osmotic type cataracts. The dose-effect curves obtained for cortical and epithelial enzymes were different. Since the data do not follow a mono-exponential function, the existence of two forms of Na-K-ATPase in the lens is discussed.
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