Pathology of the salivary glands: The contribution of electron microscopy
作者:
Irving Dardick,
Aileen P. Burford‐Mason,
期刊:
Microscopy Research and Technique
(WILEY Available online 1994)
卷期:
Volume 27,
issue 1
页码: 46-60
ISSN:1059-910X
年代: 1994
DOI:10.1002/jemt.1070270104
出版商: Wiley Subscription Services, Inc., A Wiley Company
关键词: Salivary gland;Tumor;Differentiation;Classification;Experimental studies;Electron microscopy
数据来源: WILEY
摘要:
AbstractElectron microscopy has a limited role in the diagnosis of primary salivary gland tumors, although it can be helpful in metastatic lesions of possible salivary gland origin. The diversity of subtypes in salivary gland tumors, as well as the range of histomorphology within any one subtype, is unparalleled in any other human tumor. This and their relative infrequency causes diagnostic problems for pathologists. Ultrastructural techniques have been of major importance in determining the inter‐relationship of these tumors for classification purposes, revealing the subtle variations in common cellular differentiation pathways, determining the organization of tumor cells, and displaying the importance of extracellular matrix materials in establishing diagnostic criteria for each of the many subtypes. Electron microscopy has also been valuable in non‐neoplastic salivary gland disease and has an increasing role in experimental studies involving tissue from human and animal salivary parenchyma. © 1994 Wiley‐Lis
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