A study of aromatic nitro compounds for the selection of candidates for carcinogen bioassay
作者:
C.T. Helmes,
V.A. Fung,
B. Lewin,
K.E. McCaleb,
S. Malko,
A.M. Pawlovich,
期刊:
Journal of Environmental Science and Health . Part A: Environmental Science and Engineering
(Taylor Available online 1982)
卷期:
Volume 17,
issue 1
页码: 75-128
ISSN:0360-1226
年代: 1982
DOI:10.1080/10934528209375021
出版商: Taylor & Francis Group
数据来源: Taylor
摘要:
The class of aromatic nitro compounds was studied in order to nominate chemicals to the National Cancer Institute as candidates for carcinogen bioassay. After application of several qualifying criteria relating to previous, current, or planned carcinogenicity tests and to commercial significance, the preliminary candidate list of 441 chemicals was reduced to a list of 210 chemicals. Based upon consideration of both the suspicion of possible carcinogenic activity and evidence indicating potential exposure, the following 14 chemicals were nominated: 4‐chloro‐2‐nitroaniline; 2,4‐dinitroaniline; 4‐nitroaniline; benefin; 2‐bromo‐4,6‐dinitro‐aniline; 2‐nitroanisole; nitrobenzene; 4,4'‐dinitro‐2,2'‐stilbene‐disulfonic acid; l,8‐dihydroxy‐4,5‐dinitroanthraquinone; C.I. Pigment Red 3; C.I. Pigment Orange 5; C.I. Pigment Red 23; C.I. Pigment Yellow 74; and 2‐amino‐6‐nitrobenzothiazole.
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