Cholesterol Metabolism in Gonadectomized Rats
作者:
Richard Coleman,
Yu Chen,
Roslyn Alfin-slater,
期刊:
Circulation Research
(OVID Available online 1958)
卷期:
Volume 6,
issue 2
页码: 172-177
ISSN:0009-7330
年代: 1958
出版商: OVID
数据来源: OVID
摘要:
In studies in which tissue concentrations of cholesterol and total lipids were determined in male and female rats fed a control diet containing fat, the effects of gonadectomy were much smaller than in animals fed a fat-free diet in which gonadectomy tended to reverse the sex differences observed in these lipid values. Other phases of lipid metabolism were shown to be sex-linked as well. Gonadectomy resulted in decreased synthesis of cholesterol in rat liver slices and changes in the fatty acid composition of cholesterol esters in the liver.
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