Microscopic Polyangiitis Presenting as Idiopathic Pulmonary Fibrosis:Is Anti-Neutrophilic Cytoplasmic Antibody Testing Indicated?
作者:
Ishak A. Mansi,
Adriana Opran,
Damanpaul Sondhi,
Raji Ayinla,
Fred Rosner,
期刊:
The American Journal of the Medical Sciences
(OVID Available online 2001)
卷期:
Volume 321,
issue 3
页码: 201-202
ISSN:0002-9629
年代: 2001
出版商: OVID
关键词: Microscopic polyangiitis;Anti-neutrophilic cytoplasmic antibodies (ANCA);Idiopathic pulmonary fibrosis.
数据来源: OVID
摘要:
We report a 55-year old woman with microscopic polyangiitis who presented with idiopathic pulmonary fibrosis and 1 year later developed hematuria and proteinuria. She had a high serum level of perinuclear anti-neutrophilic cytoplasmic antibodies. Renal angiogram was normal. The diagnosis of microscopic polyangiitis was confirmed by renal biopsy, which showed pauci-immune crescentic glomerulonephritis. The patient received immunosuppressive therapy and improved markedly. Consideration of small vessel vasculitis is important in the differential diagnosis of idiopathic pulmonary fibrosis.
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