Maximum likelihood and other BAN estimators have been shown to possess certain optimal asymptotic properties in estimating the parameters of probability distributions satisfying specific regularity conditions. The subject of non-regular estimation is concerned with problems in which these conditions do not hold. In many such problems, classical lower bounds on the variance of unbiased estimators, such as the Cramér-Rao bound, lead to the trivial resultV(t) ≧0, wheretis any unbiased estimator. A number of alternative bounds for application in the non-regular case have been derived. In this paper previous results of this type are reviewed and an additional bound is given. The specific applications of interest involve estimation of a location parameter. Applications of the bounds to the exponential, uniform and Pearson Type III distributions are investigated.